Drug Resistance

Guest Editors:

  • Ying Zhang (Johns Hopkins University, USA)

drug-resistanceEMI Special Topic - Drug Resistance will publish papers on antimicrobial resistance in all medically relevant bacteria, viruses, parasites and fungi including epidemiology and surveillance of resistant microbes, mechanisms of action and resistance, detection of resistance, treatment practice and strategies, and new drug development. Besides the conventional genetic drug resistance due to chromosomal mutations or mobile genetic elements, phenotypic drug resistance in microbes as in bacterial persisters and biofilms, parasites and fungi will also be included. EMI Special Topic - Drug Resistance welcomes original research reports, high quality reviews, and perspective articles that cover historical discoveries, recent advances, and future developments in the above areas.

More articles to be added soon.

Title: Identification and characterization of a novel incompatibility group X3 plasmid carrying blaNDM-1 in Enterobacteriaceae isolates with epidemiological links to multiple geographical areas in China

Authors: Pak-Leung Ho, Zhen Li, Wai-U Lo, Yuk-Yam Cheung, Chi-Ho Lin, Pak-Chung Sham, Vincent Chi-Chung Cheng, Tak-Keung Ng, Tak-Lun Que and Kin-Hung Chow

Emerg Microbes Infect 1: e39; doi:10.1038/emi.2012.37. LINK

Title: An insight into future antibacterial therapy

Authors: Alain J Cozzone

Emerg Microbes Infect 1: e38; doi:10.1038/emi.2012.35. LINK

Title: “ZS-MDR-TB” versus “ZR-MDR-TB”: Improving Treatment of MDR-TB by Identifying Pyrazinamide Susceptibility

Authors: Ying Zhang, Kwok Chiu Chang, Chi-Chiu Leung, Wing Wai Yew, Brigitte Gicquel, Dorothy Fallows, Gilla Kaplan, Richard E Chaisson and Wenhong Zhang

Emerg Microbes Infect 1: e5; doi:10.1038/emi.2012.18 LINK

Title: Indian TB cases highlight need for drug-resistance tests

Authors: Hersher R

Nat Med. 2012 Mar 6; 18(3):333. doi: 10.1038/nm0312-333. LINK

Title: Advancing the development of tuberculosis therapy

Authors: Zumla A, Hafner R, Lienhardt C, Hoelscher M, Nunn A

Nat Rev Drug Discov. 2012 Mar 1; 11(3):171-2. doi: 10.1038/nrd3694. LINK

Title: High-throughput decoding of antitrypanosomal drug efficacy and resistance

Authors: Alsford S, Eckert S, Baker N, Glover L, Sanchez-Flores A, Leung KF, Turner DJ, Field MC, Berriman M, Horn D

Nature. 2012 Jan 25; 482(7384):232-6. doi: 10.1038/nature10771. LINK

Title: Call of the wild: antibiotic resistance genes in natural environments

Authors: Allen HK, Donato J, Wang HH, Cloud-Hansen KA, Davies J, Handelsman J

Nat Rev Microbiol. 2010 Apr; 8(4):251-9. doi: 10.1038/nrmicro2312. Epub 2010 Mar 1. LINK

Title: Anti-virulence strategies to combat bacteria-mediated disease

Authors: Rasko DA, Sperandio V

Nat Rev Drug Discov. 2010 Feb; 9(2):117-28. doi: 10.1038/nrd3013. Epub 2010 Jan 18. LINK

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