NEWS & VIEWS

1 Traditional passive immune therapy for emerging Ebola infection - Peter J Lachmann

COMMENTARIES

2 EV71 vaccines: a milestone in the history of global vaccine development - Shan Lu

3 Lessons to be learned from the ebolavirus outbreak in West Africa - Hans-Dieter Klenk

4 Using convalescent whole blood or plasma as passive immune therapy for the global war against Ebola - Shan Lu

LETTERS TO THE EDITOR

5 Detection of Rickettsia amblyommii in ticks collected from Missouri, USA - Meghan Hermance, Rodrigo I Marques dos Santos, Dar Heinze, Nicole Hausser, Donald H Bouyer and Saravanan Thangamani

6 The quest for effective Ebola treatment: Ebola VP35 is an evidence-based target for dsRNA drugs - William M Mitchell and William A Carter

CASE REPORTS

7 Co-infection of visceral leishmaniasis and HIV-1: a surviving case in China and review of treatment strategies - Shihui Song, Xi’en Gui and Liren Guan

8 Emergence of human babesiosis along the border of China with Myanmar: detection by PCR and confirmation by sequencing - Xia Zhou, Sheng-Guo Li, Jia-Zhi Wang, Ji-lei Huang, He-Jun Zhou, Jun-Hu Chen and Xiao-Nong Zhou

REVIEWS

9 Persisters, persistent infections and the Yin-Yang Model - Ying Zhang

10 CsgD regulatory network in bacterial traits-altering biofilm formation - Zhen Liu, Hua Niu, Shuyan Wu and Rui Huang

11 Host adaptation and transmission of influenza A viruses in mammals - Eefje JA Schrauwen and Ron AM Fouchier

12 Three decades of USAID investments in immunization through the child survival revolution - Richard Murray Trostle and Angela K Shen

13 The impact of drug resistance on Mycobacterium tuberculosis physiology: what can we learn from rifampicin? - Anastasia Koch, Valerie Mizrahi and Digby F Warner

14 Natural reservoirs for homologs of hepatitis C virus - Stephanie Pfaender, Richard JP Brown, Thomas Pietschmann and Eike Steinmann

15 Molecular basis of host specificity in human pathogenic bacteria - Xiaolei Pan, Yang Yang and Jing-Ren Zhang

16 The saga of XMRV: a virus that infects human cells but is not a human virus - Maribel Arias and Hung Fan

17 Streptococcus suis, an important pig pathogen and emerging zoonotic agent – an update on the worldwide distribution based on serotyping and sequence typing - Guillaume Goyette-Desjardins, Jean-Philippe Auger, Jianguo Xu, Mariela Segura and Marcelo Gottschalk

18 The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections - Adrian Egli, Deanna M Santer, Daire O’Shea, D Lorne Tyrrell and Michael Houghton

19 Receptors for enterovirus 71 - Seiya Yamayoshi, Ken Fujii and Satoshi Koike

20 Oncogenes and RNA splicing of human tumor viruses - Masahiko Ajiro and Zhi-Ming Zheng

21 Persistence of hepatitis B virus covalently closed circular DNA in hepatocytes: molecular mechanisms and clinical significance - Hung-Chih Yang and Jia-Horng Kao

22 Regulatory science accelerates the development of biotechnology drugs and vaccines by NIFDC - Zhenglun Liang, Qunying Mao, Yiping Wang, Changgui Li, Kai Gao and Junzhi Wang

23 Russian vaccines against especially dangerous bacterial pathogens - Valentina A Feodorova, Lidiya V Sayapina, Michael J Corbel and Vladimir L Motin

ORIGINAL ARTICLES

24 Exploration of risk factors contributing to the presence of influenza A virus in swine at agricultural fairs - Andrew S Bowman, Jeffrey D Workman, Jacqueline M Nolting, Sarah W Nelson and Richard D Slemons

25 A gorilla reservoir for human T-lymphotropic virus type 4 - Matthew LeBreton, William M Switzer, Cyrille F Djoko, Amethyst Gillis, Hongwei Jia, Michele M Sturgeon, Anupama Shankar, Haoqiang Zheng, Gerard Nkeunen, Ubald Tamoufe, Ahmadou Nana, Joseph Le Doux Diffo, Babila Tafon, John Kiyang, Bradley S Schneider, Donald S Burke and Nathan D Wolfe

26 Multiple introductions of highly pathogenic avian influenza H5N1 viruses into Bangladesh - Atanaska Marinova-Petkova, Mohammed M Feeroz, SM Rabiul Alam, M Kamrul Hasan, Sharmin Akhtar, Lisa Jones-Engel, David Walker, Laura McClenaghan, Adam Rubrum, John Franks, Patrick Seiler, Trushar Jeevan, Pamela McKenzie, Scott Krauss, Richard J Webby and Robert G Webster

27 Saffold virus is able to productively infect primate and rodent cell lines and induces apoptosis in these cells - Yishi Xu, Carla Bianca Luena Victorio, Qimei Ng, Yee Joo Tan and Kaw Bing Chua

28 Association of gyrA/B mutations and resistance levels to fluoroquinolones in clinical isolates of Mycobacterium tuberculosis - Jing Li, Xu Gao, Tao Luo, Jie Wu, Gang Sun, Qingyun Liu, Yuan Jiang, Yangyi Zhang, Jian Mei and Qian Gao

29 When climate change couples social neglect: malaria dynamics in Panamá - Lisbeth Amarilis Hurtado, Lorenzo Cáceres, Luis Fernando Chaves and José E Calzada

30 Neutralizing antibody responses to enterovirus and adenovirus in healthy adults in China - Xiang Wang, Man Xing, Chao Zhang, Yong Yang, Yudan Chi, Xinying Tang, Hongbo Zhang, Sidong Xiong, Luogang Yu and Dongming Zhou

31 Emerging sporotrichosis is driven by clonal and recombinant Sporothrix species - Anderson Messias Rodrigues, GSybren de Hoog, Yu Zhang and Zoilo Pires de Camargo

32 A neonatal gnotobiotic pig model of human enterovirus 71 infection and associated immune responses - Xingdong Yang, Guohua Li, Ke Wen, Tammy Bui, Fangning Liu, Jacob Kocher, Bernard S Jortner, Marlice Vonck, Kevin Pelzer, Jie Deng, Runan Zhu, Yuyun Li, Yuan Qian and Lijuan Yuan

33 A novel MLST sequence type discovered in the first fatal case of Laribacter hongkongensis bacteremia clusters with the sequence types of other human isolates - Cindy WS Tse, Shirly OT Curreem, Ingrid Cheung, Bone SF Tang, Kit-Wah Leung, Susanna KP Lau and Patrick CY Woo

34 Genetic diversity of Streptococcus pneumoniae causing meningitis and sepsis in Singapore during the first year of PCV7 implementation - Elita Jauneikaite, Johanna Mary Carnon Jefferies, Nicholas William Vere Churton, Raymond Tzer Pin Lin, Martin Lloyd Hibberd and Stuart Charles Clarke

35 Assessing control bundles for Clostridium difficile: a review and mathematical model - Laith Yakob, Thomas V Riley, David L Paterson, John Marquess and Archie CA Clements

36 Identification of novel activity against Borrelia burgdorferi persisters using an FDA approved drug library - Jie Feng, Ting Wang, Wanliang Shi, Shuo Zhang, David Sullivan, Paul G Auwaerter and Ying Zhang

37 Characterisation of a G1P[8] rotavirus causing an outbreak of gastroenteritis in the Northern Territory, Australia, in the vaccine-era - Celeste M Donato, Daniel Cowley, Thomas L Snelling, Asmik Akopov, Ewen F Kirkness and Carl D Kirkwood

38 Complex temporal climate signals drive the emergence of human water-borne disease - Aaron Morris, Rodolphe E Gozlan, Hossein Hassani, Demetra Andreou, Pierre Couppié and Jean-François Guégan

39 Aspartate decarboxylase PanD as a new target of pyrazinamide in Mycobacterium tuberculosis - Wanliang Shi, Jiazhen Chen, Jie Feng, Peng Cui, Shuo Zhang, Xinhua Weng, Wenhong Zhang and Ying Zhang

40 The vaccine potential of Bordetella pertussis biofilm-derived membrane proteins - Daan de Gouw, Diego O Serra, Marien I de Jonge, Peter WM Hermans, Hans JCT Wessels, Aldert Zomer, Osvaldo M Yantorno, Dimitri A Diavatopoulos and Frits R Mooi

41 The approved pediatric drug suramin identified as a clinical candidate for the treatment of EV71 infection—suramin inhibits EV71 infection in vitro and in vivo - Peijun Ren, Gang Zou, Benjamin Bailly, Shanshan Xu, Mei Zeng, Xinsheng Chen, Liang Shen, Ying Zhang, Patrice Guillon, Fernando Arenzana-Seisdedos, Philippe Buchy, Jian Li, Mark von Itzstein, Qihan Li and Ralf Altmeyer

42 Burkholderia pseudomallei in soil samples from an oceanarium in Hong Kong detected using a sensitive PCR assay - Susanna KP Lau, San-Yuen Chan, Shirly OT Curreem, Suk-Wai Hui, Candy CY Lau, Paul Lee, Chi-Chun Ho, Paolo Martelli and Patrick CY Woo

43 The Rift Valley fever accessory proteins NSm and P78/NSm-GN are distinct determinants of virus propagation in vertebrate and invertebrate hosts - Felix Kreher, Carole Tamietti, Céline Gommet, Laurent Guillemot, Myriam Ermonval, Anna-Bella Failloux, Jean-Jacques Panthier, Michèle Bouloy and Marie Flamand

44 Pathobiologic features of novel, highly pathogenic avian influenza AH5N8 virus - Young-Il Kim, Philippe Noriel Q Pascua, Hyeok-Il Kwon, Gyo-Jin Lim, Eun-Ha Kim, Sun-Woo Yoon, Su-Jin Park, Se Mi Kim, Eun-Ji Choi, Young-Jae Si, Ok-Jun Lee, Woo-Sub Shim, Si-Wook Kim, In-Pil Mo, Yeonji Bae, Yong Taik Lim, Moon Hee Sung, Chul-Joong Kim, Richard J Webby, Robert G Webster and Young Ki Choi

45 An adult zebrafish model for Laribacter hongkongensis infection: Koch's postulates fulfilled - Jun Xie, Jia-Bei He, Jia-Wei Shi, Qiang Xiao, Ling Li and Patrick CY Woo

46 Drug susceptibility profile and pathogenicity of H7N9 influenza virus Anhui1 lineage with R292K substitution - Xiaonan Zhang, Zhigang Song, Jing He, Hui-Ling Yen, Jianhua Li, Zhaoqin Zhu, Di Tian, Wei Wang, Lei Xu, Wencai Guan, Yi Liu, Sen Wang, Bisheng Shi, Wanju Zhang, Boyin Qin, Jialin Cai, Yanmin Wan, Chunhua Xu, Xiaonan Ren, Haili Chen, Lu Liu, Yuqin Yang, Xiaohui Zhou, Wenjiang Zhou, Jianqing Xu, Xiaoyan Zhang, Malik Peiris, Yunwen Hu and Zhenghong Yuan

47 Potential impact on kidney infection: a whole-genome analysis of Leptospira santarosai serovar Shermani - Li-Fang Chou, Ting-Wen Chen, Yi-Ching Ko, Ming-Jeng Pan, Ya-Chung Tian, Cheng-Hsun Chiu, Petrus Tang, Cheng-Chieh Hung and Chih-Wei Yang

48 Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs - Jennifer Kouznetsova, Wei Sun, Carles Martínez-Romero, Gregory Tawa, Paul Shinn, Catherine Z Chen, Aaron Schimmer, Philip Sanderson, John C McKew, Wei Zheng and Adolfo García-Sastre

49 Genesis of avian influenza H9N2 in Bangladesh - Karthik Shanmuganatham, Mohammed M Feeroz, Lisa Jones-Engel, David Walker, SMRabiul Alam, MKamrul Hasan, Pamela McKenzie, Scott Krauss, Richard J Webby and Robert G Webster